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Oxidative Stress: Harms and Benefits for Human Health

Oxidative Stress: Harms and Benefits for Human Health

Oxidative stress occurs when free radicals (freie radikale) are formed in your body to dominate your body’s defences, this imbalance can lead to cell and tissue damage. Oxidative stress disproportionates the production and accumulation of reactive oxygen species (ROS) in cells and tissues and the biological system’s ability to detoxify reactive products. Cells develop ROS…

An Alternative Strategy for Fighting SARS-CoV-2 Infection

An Alternative Strategy for Fighting SARS-CoV-2 Infection

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-caused coronavirus illness 2019 (COVID-19) has been more than an infectious disease outbreak. It not only put an unprecedented burden on healthcare institutions, the global economy, and society, but it also pushed the global research community to explore novel treatment possibilities like never before.  While multiple drugs that had…

Which Controls to Use in ELISA Assays?

Which Controls to Use in ELISA Assays?

What is an ELISA? Enzyme-linked immunosorbent assay is popularly abbreviated as ELISA and has another name, enzyme immunoassay (EIA), defining the same technology. It’s a plate-based assay technique developed to discover and quantify soluble substances such as proteins, antibodies, peptides and hormones.  In an ELISA, the target macromolecule (the antigen) is palsied on a solid…

Does a Covid infection guarantee protective antibodies?

Does a Covid infection guarantee protective antibodies?

Among the most extraordinary questions of the overwhelming COVID-19 pandemic is the toughness of resistance and time to likely reinfection. There is restricted direct information on SARS-CoV-2 long-term immune responses and reinfection. Antibodies are essential for the body’s immune response to infection. Antibodies that neutralise SARS-CoV-2, which causes COVID-19, are typically recognisable in the initial…

Molecular Methods and Platforms for Infectious Diseases Testing

Molecular Methods and Platforms for Infectious Diseases Testing

Molecular assays have considerably improved the field of infectious disease diagnostics, especially with the superior responsiveness and specificity linked by presenting clinical laboratories with accurate and rapidly obtained results. Recent advancements in Molecular Diagnostics and the availability of commercial Nucleic Acid Amplification Techniques (NAATs) based assays have transformed the way researchers perform laboratory diagnosis of…

COVID-19 Treatment and Recovery

COVID-19 Treatment and Recovery

COVID-19 is known as a new viral infection. One of the vital biological characteristics of SARS-CoV-2 and various other viruses is the ubiquity of spike proteins that enable viruses to penetrate host cells and cause infection. The most significant medical concern is a secondary bacterial strain that manifests during or after a viral infection(s), leading…