rhIL-2 Recominant Human Interleukin-2Check our terms regarding shipping costs, taxes and duties
Recombinant Human Interleukin-2 (rhIL-2, previously referred to as T-Cell Growth Factor), is an important biological protein that mediates the process of clonal expansion and maintenance of T-cell proliferation. It is a recombinant protein of high specific activity and purity. The rhIL-2 originates from the IL-2 gene found in human Jurkat cell line which was cloned into E. coli. This product differs from native IL-2 in two ways. First, it is not glycosylated, and second, the protein differs at two amino acid positions (the first three N-terminal amino acids are absent, and CYS at position 125 is substituted by SER). CELLKINES rhIL-2 with a molecular weight of 15.4 kDa is formulated in 2% fetal bovine serum (heat inactivated) as a stabilizer and sterile filtered.
CELLKINES rhIL-2 is valuable in a variety of studies aimed at the mechanism of IL-2/T-cell interaction, regulation of T-cell growth cycle progression, receptor characterization and for in vitro laboratory studies of T-cell malignancies such as Adult T-cell Leukemia (ATL).