Maclura pomifera (Osage orange) Lectin (MPL/MPA) – Pure
Maclura pomifera agglutinin or lectin (MPA/MPL) is tetrameric plant protein isolated from Osage orange. MPA has a molecular weight of about 44, 000 and consists of four subunits. It has an isoelectric point between pH 4.8 and pH 5.3, and blood group specificity towards A, B, and O (-SA). This lectin has a high affinity for tumor-associated T-antigen disaccharide (Gal1, 3GalNAc) and many O-linked glycopeptide structures. The structure of Gal1, 3GalNAc occurs on the surface of tumor cells as a mucin-associated antigenic marker, termed as T-antigen. It is also the central element in O-linked glycopeptide structures on other mammalian glycoproteins. See other MPA/MPL conjugates.This product comes in a lyophilized form and is stored at -20° C. Reconstitute with sterile buffer. No metal ions are required for binding.