Pisum sativum (Pea) Lectin (PSA/PEA) – Pure
Pisum sativum lectin or agglutinin (PSA/PEA) is isolated from peas and purified by affinity chromatography. PSA has a molecular weight of around 53, 000 and is a heterodimer that consists of four subunits. It has an isoelectric point between pH 6.0 and pH 6.7. It has a carbohydrate specificity towards -mannose and -glucose with an eluting sugar of -methylglucoside + -methylmannoside. It’s hemagglutinating activity can be inhibited by glucose, mannose, and sucrose. It does not have a blood group specificity.The N-terminal sequence of the lectin has shown some degree of homology compared to lectins from other legume species. PSA has also shown mitogenic effect toward murine splenocytes and could inhibit activity of HIV-1 reverse transcriptase. See other PSA/PEA conjugates.This product comes in a lyophilized form and is stable for more than three years when stored below -20° C. Metal ions calcium and manganese are required for binding activity.