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Anti-MCM7 Antibody [MCM7/1467] – BSA and Azide free

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Mouse monoclonal [MCM7/1467] antibody to MCM7.

Applications:Flow Cytometry, IF, IHC-P, Host:Mouse, Clonality:Monoclonal, Clone ID:MCM7/1467, Isotype:IgG2a, Conjugate:Unconjugated, Reactivity:Human, Immunogen:Recombinant fragment, around amino acids 195-319, of human MCM7 protein. The exact sequence is proprietary, Specificity:The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000 full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB, Concentration:1 mg/ml, Product form:Liquid, Molecular weight:88 kDa, Formulation:Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free, Light chain:kappa, Purification:Protein A/G chromatography, Storage:Shipped at 4?C. Upon delivery aliquot and store at -20?C. Avoid freeze / thaw cycles, Recommended dilutions:Flow Cytometry: 1-2 ?g/million cells, IF: 1-2 ?g/ml, IHC-P: 1-2 ?g/ml, Target:MCM7

+25° C.


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