How does Biofire filmarray work, and what are the different types available?

How does Biofire filmarray work, and what are the different types available?

Imagine a technology that could revolutionise clinical diagnostics by providing swift and accurate results for a wide array of infectious diseases. 

The Biofire FilmArray is one such clinical tool that has transformed molecular diagnostics. Given its ability to provide rapid and precise results, it has become a vital instrument for healthcare professionals worldwide. 

But what is the Biofire FilmArray, and what does it do? 

In this article, we examine the types and functions of the Biofire FilmArray.

Helvetica Health Care (HHC) is a leading provider of external panels and run controls for BioFire FilmArray and other clinical diagnostic solutions. We offer a wide range of Quality Controls and Verification Panels in different formats (single or multiple analytes) that can be used across various molecular testing platforms and assays. 

Based on product configuration, fill volumes and concentration of analytes, using these independent controls consistently helps monitor testing performance and provides extra confidence in the quality and reliability of laboratory operations.

To know more about all the various molecular testing platforms and assays offered by us, please follow this link:

What is Biofire Filmarray?

The Biofire Filmarray System is a multiplex PCR system certified by the FDA, TGA, and CE-IVD for medical diagnostics. The process involves the assimilation of various samples for detection, amplification, preparation, and subsequent analysis. 

The Biofire FilmArray is a small, fully integrated system that combines the power of molecular biology with the ease of automation. It uses multiplex polymerase chain reaction (PCR) technology to detect and identify several infections in a single sample simultaneously.

The system is characterised by its simplicity, necessitating a mere two-minute hands-on time and an hour-long run time. These attributes contribute to its ability to yield expeditious results, thereby facilitating the provision of prompt assistance to hospitalised patients.

How does BioFire FilmArray work?

Sample Preparation:

Collecting a sample from the patient, such as a throat swab or blood sample, is the first stage. This sample is then prepared for analysis, which usually involves the extraction of nucleic acids (DNA or RNA) from pathogens present in the sample.

Multiplex Polymerase Chain Reaction (PCR): 

BioFire FilmArray uses a multiplex PCR technique that simultaneously amplifies and detects specific DNA or RNA sequences from a wide range of pathogens. This amplification process permits the detection of even minute quantities of genetic material, thereby increasing the test’s sensitivity.

Detection and Analysis: 

The BioFire FilmArray system utilises an advanced collection of molecular probes to identify and quantify amplified DNA and RNA. These probes are designed to target specific genetic sequences unique to each pathogen, ensuring the accuracy of pathogen identification.

Rapid Reporting: 

Speed is one of the primary advantages of the BioFire FilmArray. Typically, results are available within a few hours, making them useful in emergencies and for rapidly diagnosing contagious diseases.

What are the different types of Biofire Filmarray panels?

Types of Biofire Filmarray panels

Now that we better understand how BioFire FilmArray functions, let’s examine the different types of available panels, each of which is tailored to specific diagnostic requirements. BioFire provides a variety of panels designed to target specific pathogens or disease clusters, making it an adaptable tool for healthcare professionals. Here are some notable alternatives:

BioFire FilmArray Respiratory Panels:

The purpose of these panels is to detect respiratory infections. They can identify a vast array of viruses and bacteria that cause respiratory ailments, including influenza, COVID-19, and many others. For healthcare professionals, these panels can accurately and swiftly diagnose the cause of symptoms.

BioFire FilmArray Gastrointestinal Panels: 

Due to the large number of potential pathogens, gastrointestinal infections can be difficult to diagnose. BioFire’s Gastrointestinal Panels can identify a wide range of viruses, bacteria, and parasites responsible for GI problems, facilitating prompt and accurate treatment.

BioFire FilmArray Meningitis/Encephalitis Panels: 

The focus of these panels is the identification of pathogens that induce infections of the central nervous system. They help medical professionals provide appropriate treatment while preventing severe complications with a prompt diagnosis.

BioFire FilmArray Pneumonia Panels:

Pneumonia is a prevalent and occasionally fatal lung infection. BioFire FilmArray panels help identify the causative agents quickly, which is vital in determining the most effective antibiotics for treatment.

These specially designed BioFire FilmArray panels are vital in optimising Lab efficiency. To learn more about how this system enhances lab outputs, please read our previous article – 5 Tips for Optimal Lab Efficiency with BioFire FilmArray.”

Contact us today and let us know how we can help your labs.