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Comprehensive Range of Monoclonal and Polyclonal Antibodies for Diverse Applications High-Specificity Antibodies for Research and Diagnostics
We offer an extensive selection of monoclonal and polyclonal antibodies against infectious agents. Our antibodies are designed to target specific human viral proteins with high specificity, making them ideal for various immunoassays. Our MONOBODIES™ are versatile and can be used in applications such as ELISA, immunoblotting, and immunochemistry.
What Are Antibodies?
Antibodies, also known as Immunoglobulins (IgG), are proteins found in the serum. These serum proteins belong to a group called gamma globulins and are produced by the immune system in response to antigens. Antigens are harmful substances such as germs, pathogens, or other foreign entities that can disrupt normal bodily functions. Antibodies play a crucial role in identifying and neutralizing these antigens.
Monoclonal Antibodies (MABs)
Monoclonal antibodies are monospecific antibodies produced by identical immune cells, clones of a unique parent cell. These antibodies are a natural part of the immune response to germs, vaccines, and other foreign bodies. MABs offer several advantages over polyclonal antibodies due to their homogeneity and binding specificity. Because they detect a single target epitope, MABs are less likely to cross-react with other proteins, providing high precision in research and diagnostics.
Polyclonal Antibodies
Polyclonal antibodies consist of a mixture of antibodies produced by different B cell lines within the body. These antibodies recognize and bind to multiple epitopes on a single antigen, offering a more robust response. Polyclonal antibodies are often used in applications where detecting a range of antigens is necessary.
Key Differences: Polyclonal Antibody vs. MonoclonalAntibody
Specificity: Monoclonal antibodies target a single epitope, while polyclonal antibodies bind to multiple epitopes on an antigen.
Production: Monoclonal antibodies are produced using hybridoma technology, whereas polyclonal antibodies are derived from immunized animals.
Applications: Monoclonal antibodies are used in precise diagnostics and treatments, while polyclonal antibodies are favored for detecting a range of antigens in research.
Common Applications of Antibodies
Common Applications of Antibodies
Both monoclonal and polyclonal antibodies are extensively used in diagnostic tests such as ELISA, immunohistochemistry (IHC), and flow cytometry. Their ability to detect specific antigens makes them essential for accurate disease diagnosis.
Therapeutic Applications
Monoclonal antibodies are a cornerstone of modern therapeutics, used to treat cancers, autoimmune diseases, and infectious diseases. Their targeted action helps minimize side effects and improve patient outcomes.
Research Applications
In research, antibodies are crucial tools for studying protein functions, pathways, and interactions. They assist in detecting, quantifying, and isolating specific proteins from complex mixtures.
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